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An Association between Urolithiasis and Urinary Tract Infection

Gurmeet Singh Sarla

 

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ABSTRACT

Urolithiasis is one of the most common chronic kidney conditions. Bacteria have long been recognized to contribute to urinary stones. Several findings indicate a definitive association between urinary stones and bacteria, including the high rate of urinary tract infections in urinary stone patients. The presence of bacteria is associated with increased clumping of crystals, and that they stimulate incorporation of proteins into the stone matrix. The purpose of this study is to discuss the association between urinary tract infections to urolithiasis. 155 patients who presented with flank pain at the surgical outpatient department at a peripheral hospital in Nasik, Maharashtra, India over a period of 2 years between Jan 2017 to Oct 2018 were included in the study that underwent Ultrasonography studies to detect the side and site of the stone in the urinary system and urine culture test. The study concluded that Urolithiasis affects males more commonly as compared to females. The most frequent age group affected is between 31-40 years. Right-sided urolithiasis is commoner although a significant number of patients revealed bilateral urolithiasis on Ultrasound examination. Renal stones were commonest followed by lower ureteric stones. 40% of urolithiasis is associated with urinary tract infection and this association is stronger in females (21 patients (56.75%) out of 37 female patients revealed positive urine culture reports) as compared to males (41 patients (34.74%) out of 118 male patients were found to have positive urine culture tests). E. coli (51.61%) followed by Pseudomonas (20.96%) are the common pathogens in urolithiasis found to be associated with urinary tract infection.

Key words: Urolithiasis, Renal calculus, Urinary tract infection

 

 

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