Description

ABSTRACT

Suprachoroidal (SC) space offers a unique mode of drug delivery to achieve sustained delivery of therapeutics close to the source of choroidal and retinal pathology like macular edema. It is a novel route of intraocular drug administration with a better safety profile compared to intravitreal route. It bypasses the internal limiting membrane barrier and outer blood retinal barrier and can be a preferred route to target retinal pigment epithelium. It allows larger volume of drugs and longer duration of action with a safer procedure. Recent advances in technology have made it possible to image the SC space, so that it can be utilized for drug delivery and surgical procedures.

Keywords: Suprachoroidal space, Macular edema, Intravitreal injection, Drug delivery system, Blood retinal barrier